Target proteins of ganoderic acid DM provides clues to various pharmacological mechanisms

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Target proteins of ganoderic acid DM provides clues to various pharmacological mechanisms

Ganoderma fungus (Ganodermataceae) is a multifunctional medicinal mushroom and has been traditionally used for the treatment of various types of disease. Ganoderic acid DM (1) is a representative triterpenoid isolated from G. lingzhi and exhibits various biological activities. However, a universal starting point that triggers multiple signaling pathways and results in multifunctionality of 1 is...

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Ganoderma lucidum is a mushroom that has a long history of medicinal use in the Far East countries as this mushroom is revered for its supposed miracle cures and life improving properties. Recently, this mushroom has come under scientific scrutiny to examine the possibility of finding biologically active compounds that may have an impact on human physiology. The main category of biologically ac...

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ژورنال

عنوان ژورنال: Scientific Reports

سال: 2012

ISSN: 2045-2322

DOI: 10.1038/srep00905